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pyridoxal isonicotinoyl hydrazone

CAS No. 737-86-0

pyridoxal isonicotinoyl hydrazone ( PIH )

Catalog No. M20082 CAS No. 737-86-0

Pyridoxal isonicotinoyl hydrazine is a cell-permeable and relatively non-toxic iron (Fe3+) chelator that shows high iron chelation efficacy both in vitro and in vivo.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    pyridoxal isonicotinoyl hydrazone
  • Note
    Research use only not for human use.
  • Brief Description
    Pyridoxal isonicotinoyl hydrazine is a cell-permeable and relatively non-toxic iron (Fe3+) chelator that shows high iron chelation efficacy both in vitro and in vivo.
  • Description
    Pyridoxal isonicotinoyl hydrazine is a cell-permeable and relatively non-toxic iron (Fe3+) chelator that shows high iron chelation efficacy both in vitro and in vivo.
  • Synonyms
    PIH
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    iron
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    737-86-0
  • Formula Weight
    286.3
  • Molecular Formula
    C14H14N4O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 28.63 mg/mL (100 mM)
  • SMILES
    Cc1ncc(CO)c(\C=N\NC(=O)c2ccncc2)c1O
  • Chemical Name
    4-pyridinecarboxylic acid 2-[[3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinyl]methylene]hydrazide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Richardson DR et al. Pyridoxal isonicotinoyl hydrazone and its analogs: potential orally effective iron-chelating agents for the treatment of iron overload disease. J Lab Clin Med. 1998 Apr;131(4):306-15.
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